Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics for antimicrobial agents. On the basis of the concepts of pharmacokinetic modeling, it is possible to describe and predict the time course of antimicrobial effects in normal and pathophysiological conditions.

Pharmaceutical pharmacological relationships can be valuable in understanding drug work, identifying optimal dose systems, and making predictions under new or preclinical clinical conditions. Not surprisingly, drug-pharmacological modeling concepts are increasingly applied in both basic and clinical research as well as in drug development.

The book will be designed as a reference to the application of pharmaceutical-pharmacological principles to improve antimicrobial treatment, specifically pharmacotherapy, and infectious diseases. The reader will be presented on various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with the pharmacodynamics of all major groups of antibiotics, the translation of data in vitro and animal model for basic research and clinical cases in humans..